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2024年8月8日 · the concept of type i interferonopathies was postulated in early 2011 and is based on the assumption that some genetic diseases result from a disruption of this complex signaling pathway,. Monogenic type i interferonopathies are inherited heterogeneous disorders characterised by early onset of systemic and organ specific inflammation, associated with constitutive activation of type i interferons. 2025年3月22日 · I 型干扰素 （IFN-I） 信号在 系统性红斑狼疮 （SLE） 发病过程里的作用已得到充分证实。 而目前发现的单基因系统性红斑狼疮样疾病（monogenic systemic lupus erythematosus ）的主流是 自身.
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2024年12月2日 · this review provides a comprehensive update on dysregulated type i interferon production and signalling in autoinflammatory interferonopathies, monogenic systemic lupus. The study of the monogenic type i interferonopathies provides an unprecedented opportunity to define the role of type i interferons in human health and disease—through the identification of patients showing. In this article, we discuss the wide spectrum of neuroradiologic features associated with monogenic interferonopathies by reviewing the literature and illustrate these with cases from our institutions.
2025年3月22日 · 而目前发现的单基因系统性红斑狼疮样疾病（monogenic systemic lupus erythematosus ）的主流是自身炎症I 型干扰素病（autoinflammatory type I interferonopathies）。
2020年6月16日 · type i interferonopathies are monogenic autoinflammatory diseases induced by constitutive activation of type i interferon Here, we provide an overview of these diseases and describe. 2016年11月7日 · the study of the monogenic type i interferonopathies provides an unprecedented opportunity to define the role of type i interferons in human health and disease—through the.
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